Conventional Therapies Deplete Brain-Infiltrating Adaptive Immune Cells in a Mouse Model of Group 3 Medulloblastoma Implicating Myeloid Cells as Favorable Immunotherapy Targets

Medulloblastoma is the most common childhood brain cancer.Mainstay treatments of radiation and chemotherapy have not changed in decades and new treatment approaches are crucial for the improvement of clinical outcomes.To date, immunotherapies for medulloblastoma have been unsuccessful, and studies investigating the immune microenvironment of the di

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Redescription of the giant Southeast Asian millipede Spirobolus macrurus Pocock, 1893 and its assignment to the new genus Macrurobolus gen. nov. (Diplopoda, Spirobolida, Pachybolidae)

A new genus of the millipede family Pachybolidae from Southeast Asia is described: Macrurobolus gen.nov., with Spirobolus macrurus Pocock, 1893 as type species.This latter species is DNA barcoded (COI) and redescribed based on male morphological characters, which hitherto were unknown.The new Task Chair genus differs from other pachybolid genera by

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